Summary: Densely arranged N-linked glycans shield the HIV-1 envelope (Env) trimer from antibody recognition.Strain-specific breaches in this shield (glycan holes) can be targets of vaccine-induced neutralizing antibodies that lack breadth.To understand the interplay between glycan holes and neutralization breadth in HIV-1 infection, we developed a
Control and performance optimization of wireless networks of Unmanned Aerial Vehicles (UAVs) require scalable approaches that go beyond architectures based on centralized network controllers.At the same time, the performance of model-based optimization approaches is often limited by the accuracy of the approximations and relaxations necessary to so
IntroductionMalawi has made progress in expanding access to modern contraceptive methods over the last decade, including the introduction of depot-medroxyprogesterone acetate subcutaneous (DMPA-SC) in 2018.DMPA-SC offers women the option to self-inject at home and may benefit adolescents with unmet need for contraception due to its discretion.This
Abstract Background Choroidal metastasis is the most common intraocular malignancy in adults, commonly presenting in later stages of the disease and associated with poor prognosis.This is the first case to describe choroidal involvement as the sole initial metastasis of the rare biphasic pulmonary tumor.Case presentation A 42-year-old white male pa
For many years, we have faced the complications of viral hepatitis and alcohol-related liver diseases such as BODY WASH COCONUT cirrhosis, decompensation, portal hypertension, and hepatocellular carcinoma (HCC).Recently, we have seen a dynamic change in the field of hepatology.With the significant achievements in eradicating the hepatitis C virus b